产品货号：
GS4672
中文名称：
重组人CDNF
英文名称：
Recombinant Human Cerebral Dopamine Neurotrophic Factor
产品规格：
5μg
发货周期：
1～3天
产品价格：
询价
分子量：Approximately 18.3kDa,a single non-glycosylated polypeptide chain containing 161 amino acids.
储存条件：冷冻（-20℃）
概述
Cerebral dopamine neurotrophic factor(CDNF),also known as ARMET-like protein 1,is encoded by the CDNF gene in humans and widely expressed in neuronal and non-neuronal tissues.The CDNF is a novel neurotrophic factor with strong trophic activity on dopaminergic neurons comparable to that of glial cell line-derived neurotrophic factor(GDNF).Furthermore,it also prevents the 6-hydroxydopamine(6-OHDA)-induced degeneration of dopaminergic neurons.By research,CDNF might be beneficial for the treatment of Parkinsons disease.Recombinant human CDNF contains 162 amino acid residues and it shares 81%and 84%a.a.sequence identity with murine and rat CDNF.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
相关搜索：重组人CDNF，CDNF, Human
储存条件：冷冻（-20℃）
概述
Cerebral dopamine neurotrophic factor(CDNF),also known as ARMET-like protein 1,is encoded by the CDNF gene in humans and widely expressed in neuronal and non-neuronal tissues.The CDNF is a novel neurotrophic factor with strong trophic activity on dopaminergic neurons comparable to that of glial cell line-derived neurotrophic factor(GDNF).Furthermore,it also prevents the 6-hydroxydopamine(6-OHDA)-induced degeneration of dopaminergic neurons.By research,CDNF might be beneficial for the treatment of Parkinsons disease.Recombinant human CDNF contains 162 amino acid residues and it shares 81%and 84%a.a.sequence identity with murine and rat CDNF.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
| 外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
| 纯度 | ＞96%by SDS-PAGE and HPLC analyses. |
| 来源 | Escherichia coli. |
| 生物活性 | Fully biologically active when compared to standard.The ED50 as determined by a cell proliferation assay using rat C6 cells is less than 25μg/ml,corresponding to a specific activity of>40 IU/mg. |
| 成分 | Lyophilized from a 0.2μmfiltered concentrated solution in 10mMPB,150 mM NaCl,pH 6.4,3%trehalose. |
| 内毒素 | Less than 1 EU/μg of rHuCDNF as determined by LAL method. |
| 复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions. |
| 氨基酸序列 | QEAGGRPGAD CEVCKEFLNR FYKSLIDRGV NFSLDTIEKE LISFCLDTKG KENRLCYYLG ATKDAATKIL SEVTRPMSVH MPAMKICEKL KKLDSQICEL KYEKTLDLAS VDLRKMRVAE LKQILHSWGE ECRACAEKTD YVNLIQELAP KYAATHPKTE L |
相关搜索：重组人CDNF，CDNF, Human